Find the odd letter group: BYX, LPO, EVU, FUT.

LPO is the odd group.

In BYX, EVU and FUT the middle letter is the alphabet-opposite of the first, and the last is one place before it.

B pairs with Y, E with V, F with U (first + middle sum to 27), then X, U, T follow.

In LPO the opposite of L is O, but O sits last while P sits in the middle.

So the group with the opposite letter misplaced stands apart.